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Immunohistochemistry (IHC) - Complex Tumor Analysis

Our pathologists employ panels of antibodies to help resolve diagnostic problems. Each panel is carefully chosen after review of H&E slides. The panel may contain up to 25 antibodies, depending on the complexity of the tumor.

Information Sheet - IHC - Complex Tumor Analysis (PDF)

CPT Codes:

88342 or 88360 (units and CPT codes vary depending on the antibodies tested)


Specimen Requirements:
  1. Fixed Paraffin Block with Corresponding H&E:
    • Tissue should be well-fixed in formalin. If alternative fixative is used, it should be noted on the requisition.
    • 0.2 cm x 0.2 cm x 0.2 cm tissue.
    • Store specimen at room temperature (>16°C).
    • Use cold pack for transport. Be sure cold pack is not in direct contact with specimen during transport.
  2. Unstained Slides:
    • Send all slides within 6 weeks of cutting.
    • Minimum of 4 slides per antibody.
    • Precut slides from paraffin blocks in 5 micron sections.
    • Mount on Poly-L-Lysine-coated or plus (+) slides.
    • Air dry. Do not oven dry.
    • Store specimen at room temperature (>16°C).
  3. Stained Slides:
    • Only H&E or Papanicolaou-stained slides are acceptable.
  4. Body Fluids:
    • Process fluids into formalin-fixed, paraffin-embedded cell blocks or cytospin preparation.

Please Note: All immunohistochemistry-stained slides, paraffin block(s) and client H&E(s) will be returned upon completion.

Turnaround Time:

2-3 days


Client Services: Oncology/Pathology   800-447-5816

Specimen Services/Pickup:  877-246-1226