Contact Genzyme Genetics

Tel: 800-357-5744
Fax: 508-389-5549

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Infectious Agents by In Situ Hybridization (ISH)

  • Epstein Barr Virus (EBER)
  • (JC) Virus – Progressive multifocal leukoencephalopathy virus
  • HPV tissue testing:
    • Human Papilloma Virus (HPV) – Screen
    • Human Papilloma Virus (HPV) – Screen & subtype
    • Human Papilloma Virus (HPV) – Subtype only

CPT Codes:

88365 (units may vary)


Specimen Requirements:
  1. Fixed Paraffin Block with Corresponding H&E:
    • Tissue should be well-fixed in formalin. If alternative fixative is used it should be noted on the requisition.
    • 0.2 cm x 0.2 cm x 0.2 cm tissue.
    • Store specimens at room temperature (20-23.5°C).
    • Use cold pack for transport. Be sure cold pack is not in direct contact with specimen during transport.
    • Turnaround Time:
      2-4 days
  2. Unstained Slides:
    • Send all slides within 6 weeks of cutting.
    • 12-16 slides should be sent for HPV testing and 6-8 slides for JC and EBER Virus testing.
    • Precut slides from paraffin block in 5 micron sections and mounted on Poly-L-Lysine-coated or plus (+) slides.
    • Air dry. Do not oven dry.

Turnaround Time:
2-4 days

Please Note: All test slides will be returned upon completion.


Client Services: Oncology/Pathology   800-447-5816

Specimen Services/Pickup:  877-246-1226