Our Services

Breast Cancer Markers:
Technical component.

Our specialized virtual slide imaging system provides high resolution images of IHC-stained, paraffin-embedded tissue specimens and allows physicians to objectively quantify the intensities and percentage of cells stained for prognostic and therapeutic biomarkers in breast cancer.

Markers:

• ER/PR
• HER2
• Ki-67
• p53

CPT Codes:

88361-TC; 88342-TC; 88360-TC; 88365-TC

Breast Cancer Markers:

Please Note: To comply with the new HER2 guidelines, only formalin-fixed tissue samples will be accepted for HER2 IHC and FISH testing. Time to tumor fixation should be as soon as possible and time of fixation should be for 6-48 hours.

1. Fixed Paraffin Block with Corresponding H&E:
   • Tissue should be well-fixed in formalin. If alternative fixative is used, it should be noted on the requisition.
   • 0.2 cm x 0.2 cm x 0.2 cm tissue.
   • Store specimen at room temperature (20-23.5°C).
   • Use cold pack for transport. Be sure cold pack is not in direct contact with specimen during transport.
2. Unstained Slides:
   • Send all slides within 6 weeks of cutting.
   • Minimum of 4 slides for first antibody test and 2 slides for each additional stain.
   • Pre-cut 5 micron sections from paraffin blocks.
   • Mount on Poly-L-Lysine-coated or plus (+) slides.
   • Air dry. Do not oven dry.
   • Store specimens at room temperature (20-23.5°C).
   • Only H&E-stained slides are acceptable.

IHC Diagnostics:
Technical component.

Our specialized virtual slide imaging system provides high resolution images of IHC-stained, paraffin-embedded tissue specimens and allows physicians to review and interpret for diagnosis.

Markers: For a listing of specific antibodies, please see our Antibody Library (listing over 200 IHC markers).

IHC Diagnostics:

1. Fixed Paraffin Block with Corresponding H&E:
   • Tissue should be well-fixed in formalin. If alternative fixative is used, it should be noted on the requisition.
   • 0.2 cm x 0.2 cm x 0.2 cm tissue.
   • Store specimen at room temperature (20-23.5°C).
   • Use cold pack for transport. Be sure cold pack is not in direct contact with specimen during transport.
2. Unstained Slides:
   • Send all slides within 6 weeks of cutting.
   • Minimum of 4 slides for first antibody test and 2 slides for each additional stain.
   • Precut slides from paraffin blocks in 5 micron sections.
   • Mount on Poly-L-Lysine-coated or plus (+) slides.
   • Air dry. Do not oven dry.
   • Store specimen at room temperature (20-23.5°C).
   • Only H&E-stained slides are acceptable.

Please Note: All immunohistochemistry-stained slides, paraffin block(s) and client H&E(s) will be returned upon completion.

Turnaround Time:

1-2 days for each test

Client Services: Oncology/Pathology   800-447-5816

Specimen Services/Pickup:  877-246-1226