JAK2 mutation analysis utilizes genomic DNA isolated from a patient’s sample in a real-time PCR assay to detect the V617F point mutation in the JAK2 gene. This assay has been validated to detect a minimum of 1% mutant sequence in a background of normal sequence. Identification of this point mutation in the JAK2 gene now allows for reliable diagnosis, classification and potential treatment of patients with myeloproliferative disorders (MPD).
Information Sheet - JAK2 Mutation Analysis (PDF)
CPT Codes:
83891(1), 83892(1), 83896(2), 83898(1), 83912(1)
Specimen Requirements:
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Peripheral Blood:
- 1-5 ml in an EDTA (lavender-top) tube.
- Bone Marrow Aspirate:
- 2-3 ml in an EDTA (lavender-top) tube.
Turnaround Time:
4-6 days
Client Services:
Oncology/Pathology
800-447-5816
Specimen Services/Pickup:
877-246-1226