The factor II (Prothrombin) G20210A mutation is one of the genetic risk factors for thrombosis and is associated with elevated prothrombin levels. Factor II G20210A mutation analysis can help to determine predisposition to thrombotic events, and appropriateness of anticoagulant therapy. Indications for Factor II G20210A testing, as part of the screening for thrombophilia, include: venous thromboembolism (especially if in an unusual site), deep vein thrombosis during pregnancy, venous thromboembolism while on oral contraceptive, fetal death after 10 weeks gestation, fetal growth restriction and/or preeclampsia, and/or family history of stroke, pulmonary embolus, deep vein thrombosis in first degree relatives under age 50.
CPT Codes:
83891(1), 83893(2), 83894(1), 83896(2), 83898(1), 83912(1)
Specimen Requirements:
Blood:
Turnaround Time:
7-10 days
Client Services:
Reproductive/Genetics
800-848-4436
Specimen Services/Pickup:
877-246-1226